PEDIATRIC NASAL SPRAY SOLUTION: FACTORIAL DESIGN DEVELOPMENT AND EVALUATION

Formulation Development and Evaluation of Ondansetron Hydrochloride Nasal Spray

The objective of the present study was to formulate and evaluate nasal delivery system contains Ondansetron hydrochloride 4 mg/ml. Ondansetron hydrochloride loaded colloidal dispersion were prepared for nasal drug delivery using various polymers like β-cyclodextrin, hydroxyl propyl βcyclodextrin at different concentrations. The optimized formulation contains 0.02% benzalkonium chloride as a pre...

Development and evaluation of orally disintegrating tablets of Pramipexole using full factorial design

Pramipexole is the mostly prescribed drug in patients with Parkinson disease. The incidence of Parkinson disease is related to aging and mostly developed in elderly people with difficulty in swallowing or dysphagia. In the current study we aimed to develop an orally fast disintegrating tablet (ODT) of pramipexole as a preferable alternative in geriatric patients. Hence, the fast disintegration ...

Azelastine Hydrochloride 0.1% Nasal Spray Azelastine Hydrochloride 0.15% Nasal Spray

FULL PRESCRIBING INFORMATION 1 INDICATIONS AND USAGE 1.1 Allergic Rhinitis Azelastine Hydrochloride Nasal Spray 0.1% and 0.15% is indicated for the relief of the symptoms of seasonal and perennial allergic rhinitis in patients 6 years of age and older. 2 DOSAGE AND ADMINISTRATION 2.1 Seasonal Allergic Rhinitis In children 6 to 11 years of age, the recommended dose of Azelastine Hydrochloride Na...

Automating nasal spray analysis

Nasal sprays and aerosols are becoming increasingly popular methods for drug delivery. The nasal route is a non-invasive way of administering drugs with rapid uptake into the bloodstream and is considered to be important for the systematic delivery of proteins and other macromolecules. A key parameter in defining the efficiency of nasal aerosol delivery systems is the particle size distribution...

CALCINASE Nasal Spray